The Cooper family tries to take a much-needed vacation from spying, but their plans are interrupted when a wealthy socialite vanishes from their resort and K.C. is determined to find out what happened.
- Zendaya as K.C. Cooper
- Kamil McFadden as Ernie Cooper
- Trinitee Stokes as Judy Cooper
- Tammy Townsend as Kira Cooper
- Kadeem Hardison as Craig Cooper
- Jonathan Schmock as Lloyd
- Natalija Nogulich as Margaret Vandervoort
- Erin Matthews as Sarah Andrews
- Noah Crawford as Gabriel Andrews
- This was part of Disney Channel's Whodunnit Weekend.
- This was the first episode where Marisa didn't appear, making K.C. the only character to appear in every episode.
- Ernie returned from his 2 episode absence.
- Running Gag: The Cooper Family kept forgetting Ernie.
- Craig could be considered very greedy in this episode, unlike other episodes.
- August 26, 2015 (Australia)
- October 2, 2015 (Germany)
- October 11, 2015 (Latin America, Brazil)
- November 20, 2015 (Spain, Portugal)
- November 24, 2015 (Israel)
- January 28, 2016 (Turkey)
- May 7, 2016 (Hungary)
| To view the K.C. and the Vanishing Lady gallery, click here.